Approximately 1200 healthy participants aged 36 years and older will be studied by a consortium of investigators at WUSTL, Massachusetts General Hospital, UCLA and the University of Minnesota. In addition, Oxford University, with which WUSTL has executed a Data Use Agreement to allow sharing of the Limited Data Set, will…
Cohort Country: United States of America
UNITE – Understanding Neurologic Injury and Traumatic Encephalopathy Brain Bank (BU-CTE Center)
Understanding Neurologic Injury and Traumatic Encephalopathy (UNITE) Brain Bank is the largest tissue repository in the world focused on traumatic brain injury and chronic traumatic encephalopathy (CTE). It collects central nervous system tissue from donors with CTE and a history of repetitive head impacts, including contact sport athletes and military…
UAB/HudsonAlpha Families with Neurodegenerative Diseases
We collected and analyzed genomic sequencing data from individuals with clinician-diagnosed early-onset or atypical dementia and, in many cases, their family members. One hundred total patients were described. Pathogenic variants, as well as established risk variants, were returned to patients. A polygenic risk score (PRS) was calculated for Alzheimer’s patients…
The Movement Disorder Clinic (MDC)
The Movement Disorder Clinic (MDC) at Washington University in Saint Louis (St. Louis, MO, USA) recruits and assess longitudinally participants with movements disorders. The Genetics of the Parkinson’s Disease study involved longitudinal collection of biofluids, clinical assessments, neuropsychological testing, neuroimaging, and, for those willing to donate the brain upon death,…
Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD)
Postmortem brain tissue and donor metadata were obtained via the UW BioRepository and Integrated Neuropathology (BRaIN) laboratory from participants in the Kaiser Permanente Washington Health Research Institute ACT Study and the University of Washington ADRC. The study cohort was selected based solely on donor brains undergoing precision rapid procedure (optimized…
Resource for Early-onset Alzheimer’s Disease Research (READR)
The READR project recruited families assumed to be multiply affected by early-onset AD by history or autopsy across the United States. The criteria for study entry included two living siblings affected by early-onset AD, 35 years of age or older, and a third living elderly relative without cognitive impairment. We…
The Sacramento Area Latino Study on Aging (SALSA)
The Sacramento Area Latino Study on Aging (SALSA) is a population-based, prospective study of foreign and US-born Latino respondents living in the Sacramento Valley region of Northern California. The SALSA study is tracking the incidence of physical and cognitive impairment as well as dementia and cardiovascular diseases in elderly Latinos…
Brain Amyloid Cognitive Normal Elders Study (BACNE)
Please reach out to Dr. Ilyas Kamboh, University of Pittsburgh, for more information.
Human Connectome Project
Please reach out to Dr. Ilyas Kamboh, University of Pittsburgh, for more information.
The Monongahela-Youghiogheny Healthy Aging Team (MYHAT)
Mild Cognitive Impairment: A Prospective Community Study. The Monongahela-Youghiogheny Healthy Aging Team study is supported in part by the National Institute on Aging under research grant R01 AG023651. The MYHAT project seeks to describe the distribution of Mild Cognitive Impairment (MCI) and related entities, their associated features, their outcomes over…