Description
1,264 samples were sequenced at USUHS on the NovaSeq machine. FASTQ files were sent to GCAD for processing on the VCPA 1.1 pipeline. A total of 1,183 samples passed sequencing metrics and quality control checks.
Sex
Total number of samples: 1,183
Female 628 53.1 %
Male 555 46.9 %
Race
Total number of samples: 1,183
| Asian | 9 |
| Black or African American | 30 |
| White | 1,076 |
| Other | 62 |
| NA | 6 |
Ethnicity
Total number of samples: 1,183
Not Hispanic or Latino
1,085
91.7%
Hispanic or Latino
84
7.1%
Not Applicable/Not Available
14
1.2%
Diagnosis
Total number of samples: 1,255
| AD | ||
|---|---|---|
| Control | 251 | 20.0% |
| Case | 699 | 55.7% |
| Other | 13 | 1.0% |
| Unknown | 244 | 19.4% |
| 48 | 3.8% |
APOE
Total number of samples: 1,183
- 226 (0.5%)
- 2382 (6.9%)
- 2419 (1.6%)
- 33529 (44.7%)
- 34375 (31.7%)
- 44160 (13.5%)
- NA12 (1.0%)
Cohorts
- Cardiff EOAD
- Knight Alzheimer’s Disease Research Center (KGAD)
- National Centralized Repository for Alzheimer’s Disease and Related Dementias Family (NCRAD Family)
- NIA Alzheimer's Disease Research Centers (ADRC)
- Research in African-American Alzheimer’s Disease Initiative (REAAADI)
- Resource for Early-onset Alzheimer’s Disease Research (READR)
- University of Miami (MIA)