Description
Unrelated Nondemented (initially), 65 years of age or older including non‐Hispanic whites (32%), African Americans (28%), and Caribbean Hispanics from the Dominican Republic (44%). Assessments include: medical evaluation, cognitive testing, MRI, PET scan and biomarkers studies.
For more information about this cohort, see the WHICAP study.
Related Datasets
- This dataset includes sequencing data and harmonized phenotypes from cohorts sequenced by the Alzheimer’s Disease Sequencing Project and other AD and Related Dementia’s studies. Samples are processed using a common…
- Many regions of the human genome present challenges that prohibit scientists from discovering potential disease-causing mutations. We developed methods to characterize mutations in these regions to rescue mutations that are…
Related Studies
- Background An initiative in response to the National Alzheimer’s Project Act (NAPA) has been working towards new biological insights and cures for Alzheimer’s Disease (AD) since its introduction by NIH…
- Since inception of the study in 1992, over 6,000 participants have enrolled in the Washington Heights and Inwood Community Aging project (WHICAP). The cohort participants were nondemented initially, 65 years…
- Many regions of the human genome present challenges that prohibit scientists from discovering potential disease causing mutations. We developed methods to characterize mutations in these regions to rescue mutations that…
- The Genetic Studies of Alzheimer’s Disease in Caribbean Hispanics (EFIGA) is the largest collection of Caribbean Hispanic multiplex AD families recruited and longitudinally assessed worldwide. At this stage we are…
Related Sample Sets
- The initial phase of the ADSP research plan is called the Discovery Phase. Samples were selected from well-characterized study cohorts of individuals with or without an AD diagnosis and the…
- The ADSP Discovery Family-Based Extension Study: To further assess the genomes in multiply affected families, under funding provided by NHGRI, an additional 427 samples were whole genome sequenced. This included…
- The WHICAP WES study consists of a multi-ethnic cohort of 4,100 individuals followed over several years. Participants were community-living Medicare recipients 65 years and older recruited from northern Manhattan to…
- Provided here are variant calls in VCF format for 14,526 samples derived from the ADSP whole-exome and whole-genome sequencing dataset (available via DSS: NG00067).
- A total of 1,396 EFIGA cohort samples were sequenced at NYGC and USUHS using the Illumina HiSeqX platform. The BAM files were sent to GCAD for processing through the VCPA1.1…
- A total of 237 WHICAP cohort samples were sequenced at NYGC and USUHS using the Illumina HiSeqX platform. The BAM files were sent to GCAD for processing through the VCPA1.1…