Description
ADGC African American samples were sequenced at University of Miami on the HiSeq3000 machine. 3226 samples were sequenced using the Agilent WES v6 target capture kit. BAM files from hg37 build were sent to GCAD for processing on the VCPA1.1 pipeline. 2763 passed sequencing metrics and quality control.
Sex
Total number of samples: 3,158
Female
2,256
71.4 %
Male
902
28.6 %
Race
Total number of samples: 3,158
Black or African American | 3,155 |
White | 3 |
Ethnicity
Total number of samples: 3,158
Not Hispanic or Latino
3,149
99.7%
Hispanic or Latino
4
0.1%
Not Applicable/Not Available
5
0.2%
Diagnosis
Total number of samples: 3,158
Disease | ||
---|---|---|
AD | 3,158 | 100.0% |
Study Specific Diagnosis | ||
---|---|---|
Control | 1,626 | 51.5% |
Case | 1,279 | 40.5% |
Unknown | 253 | 8.0% |
APOE
Total number of samples: 3,158
- 2225 (0.8%)
- 23365 (11.6%)
- 24164 (5.2%)
- 331,209 (38.3%)
- 341,123 (35.6%)
- 44260 (8.2%)
- NA12 (0.4%)
Cohorts
- NIA Alzheimer Disease Centers (ADC)
- Genetic and Environmental Risk Factors for Alzheimer’s Disease Among African Americans (GenerAAtions)
- Religious Orders Study/Memory and Aging Project (ROSMAP)
- Minority Aging Research Study (MARS)
- University of Miami (MIA)
- Multi-Institutional Research in Alzheimer’s Genetic Epidemiology (MIRAGE)
- Vanderbilt University (VAN)
Array
(
[0] => 972
[1] => 1012
[2] => 996
[3] => 1000
[4] => 957
[5] => 1524
[6] => 955
)
;